Congenital abnormalities that affect the upper lip and the hard and soft palate. Features range from a small notch in the lip to a complete fissure (groove) extending into the roof of the mouth and nose. These features may occur separately or together.

Causes, incidence, and risk factors

Cleft lip and palate are facial and oral malformations that may occur separately or together. They may also occur in association with other syndromes or birth defects. The cause of these malformations may be mutant genes or teratogens (an agent that causes abnormalities in a developing fetus, such as certain viruses or chemicals). As well as being disfiguring, these abnormalities can cause feeding difficulties, problems with speech development, and ear infections. Risk factors include a family history of cleft lip or palate and presence of another birth defect. The incidence of cleft lip and palate varies with different races; approximately 1 out of 1,000 Caucasians are affected. The incidence of cleft palate alone is 1 out of 2,500 people.

Signs and tests

Physical examination of the mouth, nose and palate confirms the presence of cleft lip or cleft palate. Diagnostic testing may be performed to determine or rule out the presence of other abnormalities.

Treatment

Treatment of cleft lip and palate requires a team approach and involves several specialties, including plastic surgeons, orthodontics, speech therapists and others. Treatment may extend over a period of several years. Surgery to close the cleft lip usually performed at 3-6 months of age. Later surgery may be needed if there is extensive nasal involvement. A cleft palate is usually closed within the first year of life to enhance normal speech development. Until surgery, a prosthetic device is often fitted over the palate for feeding. Continued follow-up may be needed with speech therapists and orthodontists.

Support groups

The stress of illness can often be helped by joining a support group where members share common experiences and problems. See cleft palate - support group .

Expectations (prognosis)

Although treatment may extend over several years and require several surgeries depending upon the involvement, most children affected by this disorder can achieve normal appearance, speech, and eating. For some, speech problems may continue.

Complications

Calling your health care provider

Cleft lip and palate is usually diagnosed at birth. Follow the health care provider's recommendations for follow-up visits. Call if problems arise between visits.

Prevention

There is no proven way to prevent this defect.